摘要
Abstract
Objective To discuss effect of rosuvastatin combined with probucol on carotid atherosclerotic plaque for infarction. Methods Selected 60 cases with infarction were randomly divided into joint group (30 cases) and control group (30 cases). Joint group was treated with rosuvastatin and probucol, and control group was treated with rosuvastatin. IMT, plaque acoustic densitometry of two groups were compared, and lipid and hs-CRP levels were detected before and after treatment. Results TC, TG, LDL-C, hs-CRP of two groups after treatment were lower than before treatment, while HDL-C was higher (P<0.01). After treatment, TC, TG, LDL-C, hs-CRP of joint group were lower than control group, and HDL-C was higher than that in the control group (P<0.01). IMT of two groups after treatment were lower than that in the before treatment (P<0.01) and IMT of joint group was lower than that in the control group; Low density acoustic echo plaques of two groups after treatment were higher than before treatment (P<0.01); High densi ty acoustic echo plaques of joint group after treatment was higher than before treatment(P<0.01) while the control group was not obvi-ously; After treatment, acoustic echo plaques of jiont group were higher than control group (P<0.01). Conclusion Ro-suvastatin associated with probucol for infarction patients can significantly improve blood lipid levels, stabilize carotid atherosclerotic plaque, and inhibit inflammation effect.关键词
瑞舒伐他汀/普罗布考/脑梗死/颈动脉粥样硬化斑块Key words
Rosuvastatin/Probucol/Infarction/Carotid atherosclerotic plaque分类
医药卫生
