摘要
Abstract
Objective To investigate the effects of different pre injection interval on rocuronium onset time. Methods A total of 92 patients who were done general anesthesia hypogastrium operation were selected. According to random digits table method,they were divided into group A,group B,group C and group D,with 23 patientes in each group. All pa-tients were injected atropine, group A, group B and group C were all intravenous driped rocuronium in advance.They were respectively intravenous driped rocuronium after one minute, two minutes, three minutes. Group D were intra-venous driped isometric normal saline,they were intravenous driped rocuronium 3 min after injection of isometric nor-mal saline. The changes of mean arterial pressure, heart rate at different time points, and the T1 value,TOF value,on-set time,condition assessment of trachea cannula and adverse reaction of patients were compared among four groups. Results The mean arterial pressure at T2, T3 in group A, group B,group C was significantly lower than that at T2, T3 in group D(P<0.05). But mean arterial pressure and the heart rate in group C was significantly lower than that in group A and group B (P<0.05). The T1 value,TOF value,onset time in group B,group C were significantly lower than those in group D (P<0.05),The T1 value,TOF value,onset time in C group were significantly lower than those in group A and group B (P<0.05). Proportion of good of tracheal intubation assessment in group A, group B and group C was significantly higher than that in group D. Proportion of good in C group was significantly higher than that in group A, group B (P<0.05). There were no obvious breath scant and adverse reaction etc. Conclusion We should take endotracheal intubation anesthesia as far as possible to choose pre injection interval by 3 minutes, for patients with done general anesthesia hypogastrium operation.关键词
预注间期/罗库溴铵/阿托品/起效时间Key words
Pre injection interval/Rocuronium/Atropine/Onset time分类
医药卫生
