摘要
Abstract
Objective To explore the clinical application value of continuous veno-venous hemofiltration (CVVH) in patients with cerebral injury complicated with severe infection. Methods A total of 57 patients with cerebral injury complicated with severe infection who were admitted to our hospital from April 2011 to April 2014 were retrospectively analyzed. They were given CVVH combined with medicinal treatment or pharmacological method respectively. The im-provement of clinical symptoms and prognosis were compared. Each clinical index before and after the treatment (body temperature, mean arterial pressure, white cell count, CRP, PaO2/FiO2, conditions of complications), APACHE II scores and 28-d mortality rate were compared between the two groups. Results Under the conditions that ages, gender, A-PACHEII scores, number of organ failure and the rate of mechanical ventilation were not significantly different, CVVH treatment was applied, and the serum CRP, white cell count, body temperature, and 28 d mortality were significantly different from those in the group who was not given the CVVH treatment. Conclusion CVVH improves the clinical symptoms of patients with cerebral injury complicated with severe infection, and anti-coagulation without heparin does not significantly improve patients' risk of bleeding. The application of CVVH is able to improve the successful rate of rescue for such type of patients.关键词
静-静脉血液滤过/脑损伤/严重感染Key words
Continuous veno-venous hemofiltration (CVVH)/Cerebral injury/Severe infection分类
医药卫生
