摘要
Abstract
Objective:To observe the clinical effects of target-controlled infusion of Propofol combined with Sufentanil for maintain anesthesia in cardiac surgery.Method:46 cases underwent heart surgery from January 2010 to June 2012 were divided into the observation group(23 cases) and control group(23 cases), by random number table.In the observation group,general anesthesia were induced and maintained by target-controlled infusion of Sufentanil and Propofol,in the control group,anaesthesia was managed with Propofol by a continuous infusion and Sufentanil intravenously after induction.Heart rate,mean arterial blood pressure values change at operating room(T1),induced immediate(T2),intubation (T3),sternotomy(T4),off the sternum(T5) were analysed.Result:About heart rates at T1,T2,T5,there were not statistically significant(P>0.05).Average heart rates at T3,T4 in the observation group were (64.4±11.7) bpm and 68.2±9.2)bpm,these were lower than those in the control group,there were statistically significant (P<0.05).About mean arterial pressure at T1,T2,T5,there were not statistically significant(P>0.05).Mean arterial blood pressure at T3,T4 in the observation group were (76.9±11.5)mm Hg and (78.1±11.7)mm Hg,these were lower than those in the control group,and there were statistically significant(P<0.05).Compared with control group,observation group showed earlier tracheal decannulation,shorter ICU stay length(P<0.05).Conclusion:Considering about the blood pressure and heart rate changes during anesthesia,Propofol combined with Sufentanil for target controlled infusion is more excellent in cardiac surgery,is worthy of application.关键词
丙泊酚/舒芬太尼/靶控输注/心脏手术Key words
Propofol/Sufentanil/Target controlled infusion/Cardiac surgery分类
医药卫生
