中外医学研究Issue(18):21-22,2.
血尿酸浓度与急性缺血性脑卒中的相关性分析
Analysis of the Relationship between Serum Uric Acid Levels and Acute Ischemic Stroke
摘要
Abstract
Objective:To investigate the relationship between serum uric acid(SUA) levels and acute ischemic stroke(AIS).Method:The case-control study was conducted to examine uric acid in 153 patients with ischemic stroke(observation group) and 110 outpatients(control group).National Institutes of Health Stroke Scale(NIHSS) score was evaluated stroke severity.Spearman rank correlation was used to analyze the relationship between SUA and AIS.Result:(1)Mean serum uric acid levels in observation group were (347.09±101.45)μmol/L,and 31.37%were hyperuricemia(HUA),they were significantly higher than those in control group(P<0.05).(2)In observation group,NIHSS score of HUA patients were higher than normal uricemia patients,and were proved statistically significant(P<0.05). Spearman rank correlation analysis showed that SUA was positive correlated with the NIHSS score in 153 patients with AIS(r=0.206,P<0.01).Conclusion:The high levels of SUA and prevalence of hyperuricemia were in patients with AIS.These findings suggest that elevated serum uric acid level can be considered as a risk factor for AIS.关键词
缺血性脑卒中/血尿酸Key words
Acute ischemic stroke/Uric acid分类
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郑开化,李新强..血尿酸浓度与急性缺血性脑卒中的相关性分析[J].中外医学研究,2014,(18):21-22,2.