中外医学研究Issue(27)：5-7,3.
16例儿童肾病综合征型紫癜性肾炎临床与病理分析
Clinical and Pathological Analysis of Childhood Henoch-Schonlein Purpura Nephritis with Nephritic Syndrome
摘要
Abstract
Objective:To investigate the relationship between clinical and renal pathologic in childhood Henoch-Schonlein purpura nephritis with nephritic syndrome.Method:Retrospective review of the clinical data and renal pathologic of 16 cases of childhood Henoch-Schonlein purpura nephritis with nephritic syndrome who had been performed renal biopsy.Result:(1) Among the pathological grading of glomeruli, we found grade Ⅲb 14 cases (87.5%), gradeⅡb and grade Ⅳb 1 case respectively (6.25%).7 cases were macrohematuria including grade Ⅲb(6 cases,85.7%) and grade Ⅳb(1 case,14.3%).9 cases were microhematuria including grade Ⅲb(8 cases,89.0%) and gradeⅡb(1 case,11.0%).Among 9 cases renal damage of tubulointersitial,there were 6 cases(66.7%) with macrohematuria and 3 cases with microhematuria.(2)Diffuse mesangial proliferation(13 cases,81.25% ) was the most common pathological pattern,7 cases were combining with crescent(macrohematuria 85.7%),4 cases were endocapillary proliferation(macrohematuria 75.0%),4 cases were capillary loops necrosis(macrohematuria 75.0%).(3)IgA+IgM as same as IgA+IgG+IgM deposit(43.75%) was the most common immune pathological grade Ⅲb andⅣb.Conclusion:Renal pathological grade Ⅲ is the most common type in childhood Henoch-Schonlein purpura nephritis with nephritic syndrome,which is often associated with severe clinical manifestations and pathological changes.Early renal biopsy is very important to make treatment plan.关键词
紫癜性肾炎/肾病综合征/儿童/肾脏病理Key words
Henoch-schonlin purpura nephritis/Nephritic syndrome/Children/Renal pathology分类
医药卫生引用本文复制引用
徐海霞,邵晓珊,李宇红,蒋新辉,应蓓,邱杰,黄艳..16例儿童肾病综合征型紫癜性肾炎临床与病理分析[J].中外医学研究,2014,(27):5-7,3.基金项目
贵州省科技厅社会发展课题(项目编号黔科合SY字[2011]3061号) （项目编号黔科合SY字[2011]3061号）
