中外医学研究Issue(30)：22-23,2.
基于生存分析的肝动脉灌注化疗预防胃癌肝转移的临床研究
Clinical Investigation on Hepatic Artery Infusion Chemotherapy for Prevention of Liver Metastasis of Gastric Carcinoma Based on Survival Analysis
许宇彪 1李碧锦 1何二松 1韦新理 1林昌荣 1莫凯迪1
作者信息
- 1. 广西壮族自治区江滨医院 广西 南宁 530021
- 折叠
摘要
Abstract
Objective:To evaluate the value of hepatic artery infusion chemotherapy for the prevention of liver metastasis from gastric carcinoma after radical operation for carcinoma of stomach.Method:According to the different treatment methods,31 cases without liver,lung,brain metastasis of distant organs in patients with gastric carcinoma were randomly divided into treatment group and control group,the treatment group were treated with hepatic artery infusion chemotherapy while the control group underwent peripherally inserted central catheter chemotherapy,and the survival time without liver metastasis was compared. Result:In the treatment group,the average survival time without liver metastasis was (23.3±2.1)months,while in the control group,the average survival time without liver metastasis was (18.5±2.6)months.There were statistically significant differences between the two groups(t=5.732,P<0.05).The survival curves of two groups by the endpoint of liver metastasis had statistically significant difference (Log-Rank χ²=17.791,P<0.05).Conclusion:Compared with the conventional intravenous chemotherapy,hepatic artery infusion chemotherapy after radical resection of colon cancer can effectively delay the liver metastasis after radical resection radical operation for carcinoma of stomach,and is a modus operandi for the prevention of liver metastases from gastric carcinoma.关键词
胃癌/肝动脉灌注化疗/肝转移/预防/生存分析Key words
Gastric carcinoma/Hepatic artery infusion chemotherapy/Liver metastasis/Prevention/Survival analysis分类
医药卫生引用本文复制引用
许宇彪,李碧锦,何二松,韦新理,林昌荣,莫凯迪..基于生存分析的肝动脉灌注化疗预防胃癌肝转移的临床研究[J].中外医学研究,2014,(30):22-23,2.
