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rt-PA联合必存静脉溶栓治疗急性脑梗死的疗效观察

陈春燕 张燕 陆学胜

中外医学研究Issue(35):3-4,2.
中外医学研究Issue(35):3-4,2.

rt-PA联合必存静脉溶栓治疗急性脑梗死的疗效观察

The Clinical Observation of Tissue-type Plasminogen Activator for Intravenous Thrombolysis Combined with Edaravone in the Treatment of Acute Cerebral Infarction

陈春燕 1张燕 1陆学胜1

作者信息

  • 1. 上海市同仁医院 上海 200336
  • 折叠

摘要

Abstract

Objective:To investigate the clinical efficacy of rt-PA for intravenous thrombolysis combined with Edaravone in the treatment of acute cerebral infarction.Method:200 patients with acute cerebral infarction in our hospital from January 2010 to December 2013 were selected,they were divided into the group A,B,C and D according to the random number table method,50 cases in each group.The group A was given rt-PA for intravenous thrombolysis combined with Edaravone,the group B was given rt-PA for intravenous thrombolysis combined with conventional treatment,the group C was given Edaravone and conventional treatment,the group D was only given conventional treatment.The clinical efficiency of four groups were compared after 14 days treatment.Result:After treatment, the total effective rate of group A was 96.0%(48/50),it was significantly higher than the other three groups,the differences were statistically significant(P<0.05). The total effective rate of group B and group C were 84.0%(42/50) and 66.0%(33/50),respectively,which were significantly higher than 46.0%(23/50) of group D, and the total effective rate of group B was significantly higher than group C,the differences were statistically significant(P<0.05).Conclusion:Application of rt-PA for intravenous thrombolysis combined with Edaravone in the treatment of early acute cerebral infarction patients has the safety and effectiveness,can improve the prognosis of patients to the maximum extent,is worthy of clinical application and promotion.

关键词

急性脑梗死/rt-PA/必存/静脉溶栓

Key words

Acute cerebral infarction/rt-PA/Edaravone/Intravenous thrombolysis

分类

医药卫生

引用本文复制引用

陈春燕,张燕,陆学胜..rt-PA联合必存静脉溶栓治疗急性脑梗死的疗效观察[J].中外医学研究,2014,(35):3-4,2.

中外医学研究

1674-6805

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