中外医学研究Issue(10)：1-2,3,3.DOI:10.14033/j.cnki.cfmr.2015.10.001
国产比伐芦定在急性心肌梗死患者介入治疗术后的疗效
Effects of Bivalirudin on Acute Myocardial Infarction for Percutaneous Coronary Intervention
贾风顺 1张宇 2费建国 2马威 2孙淑娴 2曾春燕 1李娜 3李志国 1纪征2
作者信息
- 1. 河北联合大学研究生院 河北 唐山 063000
- 2. 唐山工人医院
- 3. 河北医大研究生院
- 折叠
摘要
Abstract
Objective:To evaluate the benefit of Bivalirudin on acute myocardial infarction for percutaneous coronary intervention.Method:A total of 122 AMI patients receiving PCI were divided into two groups,Heparin group(n=55) and Bivalirudin group(n=67).We compared the procedural success rate,creatinine,ST segment percentage fall back,platelet and NT-porBNP.The safety evaluation were the incidence of bleeding and major adverse cardiac events(MACE) within 30 days of PCI.Result:ST segment percentage fall back was similar at 1-hour after the PCI procedure between two groups(P>0.05).Bivalirudin group had higher NT-porBNP levels than Heparin group before the procedure(P=0.097>0.05),however,those in two groups were similar,Bivalirudin group had lower NT-porBNP levels than Heparin group at 24-hour after the procedure(P>0.05).The mild bleeding rate during two groups were meaningful(P=0.002<0.05).The levels of platelet and creatinine at 24-hour after the PCI,the procedural success rate and the survival rate within 30 days were similar(P>0.05).Conclusion:Bivalirudin is safe and effective during emergent PCI,bleeding rate is less than Heparin.关键词
心肌梗死/比伐芦定/肝素Key words
Acute myocardial infarction/Bivalirudin/Heparin分类
医药卫生引用本文复制引用
贾风顺,张宇,费建国,马威,孙淑娴,曾春燕,李娜,李志国,纪征..国产比伐芦定在急性心肌梗死患者介入治疗术后的疗效[J].中外医学研究,2015,(10):1-2,3,3.
