中外医学研究Issue(19)：8-10,3.DOI:10.14033/j.cnki.cfmr.2015.19.004
吉西他滨联合奈达铂化疗治疗50例鼻咽癌肺转移的临床疗效分析
Clinical Effect Analysis of Gemcitabine Combined with Nedaplatin Chemotherapy on Treating 50 Cases of Lung Metastases Transform Nasopharyngeal Carcinom a
高天生 1范小玲 1李庚 1董志荣 1吴慧慧1
作者信息
- 1. 梧州市红十字会医院 广西 梧州 543002
- 折叠
摘要
Abstract
Objective:To observe and analyze the curative effect of Gemcitabine combined with Nedaplatin chemotherapy on treating 50 cases of lung metastases transform nasopharyngeal carcinoma.Method:90 patients were divided into Gemcitabine combined with Nedaplatin chemotherapy group(GN group) and Cisplatin,5-fluorouracil combined with Docetaxel chemotherapy group(PTF group),the clinical effect and adverse reactions of two groups were retrospective analyzed.Result:The effective rate of GN group was 70.0%,there was obviously improved compared with the PTF group(45.0%),the difference was statistically significant(P<0.05).The two group’s disease control rates were 94.0% and 80.0%,with no significant difference(P>0.05).GN group’s leukopenia and thrombocytopenia grade Ⅲ-Ⅳ incidence rate were lower than than those of PTF group(P<0.05).Conclusion:Gemcitabine combined with Nedaplatin chemotherapy can further improve the prognosis of patients with nasopharyngeal carcinoma with lung metastasis,chemotherapy related toxicity was significantly lower,and it is worthy of clinical application.关键词
鼻咽癌/肺转移/化疗Key words
Nasopharyngeal carcinoma/Lung metastasis/Chemotherapy分类
医药卫生引用本文复制引用
高天生,范小玲,李庚,董志荣,吴慧慧..吉西他滨联合奈达铂化疗治疗50例鼻咽癌肺转移的临床疗效分析[J].中外医学研究,2015,(19):8-10,3.
