中医药学报Issue(4):69-71,3.
桂枝茯苓丸对子宫内膜异位大鼠腹腔液中 IL -6和 TNF -α水平的影响
Effect of Guizhi Fuling Pills on the Changes of IL -6 and TNF -αin Peritoneal Fluid of Rats with Endometriosis
摘要
Abstract
Objective: To study the effect of Guizhi Fuling pills on endometriosis of rats .Methods: Autologous grafting endometriosis rat models were established , and the successful moldel rats were randomly divided into a model group ,a danazol group, Guizhi Fuling pills low, medium and high dose groups, and a control group.After 30 days, use ELISA method to detect the rat peritoneal fluid of IL -6 and TNF -αcontents.Results: Guizhi Fuling pills high dose group could obviously reduce rat peritoneal fluid levels of IL -6 (P <0.05), high, middle dose groups could significantly re-duce the levels of TNF -αin peritoneal fluid (P <0.05 or P <0.01).Conclusion: Guizhi Fuling pills have a good effect in the treatment of endometriosis in rats .关键词
桂枝茯苓丸/子宫内膜异位症/IL -6/TNF -αKey words
Guizhi Fuling pills/Endometriosis/IL-6/TNF-α分类
医药卫生引用本文复制引用
吴修红,马艳春,何录文,朴成玉,杨恩龙,孙畅,孙晖..桂枝茯苓丸对子宫内膜异位大鼠腹腔液中 IL -6和 TNF -α水平的影响[J].中医药学报,2014,(4):69-71,3.基金项目
国家自然科学基金(81373931);黑龙江省教育厅“骨干教师支持计划”(1251G057);黑龙江省中医管理局( ZHY10-W26);哈尔滨市科技创新人才基金(2012RFLXS012);黑龙江中医药大学创新人才支持计划(2012RCD07);校基金 ()