中医药学报Issue(5)：40-43,4.
清火解毒法对实验小鼠的镇痛抗炎作用研究
Research on the Analgesic and Anti-inflammatory Effect on Mice by Clearing Fire and Detoxification Method
摘要
Abstract
Objective: From the pharmacological point of view,to explore the analgesic and anti-inflammatory effect of clearing fire and detoxification therapy.Method:Acetic acid stimulation caused the mice to pain writhing and hot plate experiment,and observe the effect on the inhibition of pain in mice by taditional Chinese medicine.Xylen induced ear e-dema in mice, comparing the auricular swelling of the mice in each group after treatment.Acetic acid induced the addi-tion of capillary permeability in mice,and observe the impact of capillary permeability in mice by taditional Chinese med-icine.Results:Reduce the number of writhing response in mice caused by acetic acid significantly(P<0.01).Increase the pain threshold in mice significantly(P<0.01).Reduce the auricular swelling and swelling rate in mice(P<0.05, P<0.01);Reduce the addition of capillary permeability in mice caused by the acetic acid (P<0.05).Conclusion:Clearing fire and detoxification therapy has some analgesic and anti-inflammatory effects.关键词
下肢丹毒/清火解毒法/药效学/镇痛/抗炎Key words
Lower limb erysipelas/Clearing fire and detoxification therapy/Pharmacodynamics/analgesia/Anti-inflam-mation分类
医药卫生引用本文复制引用
钮晓红,陆春红,张晓洁,许惠琴..清火解毒法对实验小鼠的镇痛抗炎作用研究[J].中医药学报,2014,(5):40-43,4.基金项目
江苏省中医药科技项目（编号LZ09092）；南京市医学重点科技发展项目 （）
