中医药学报Issue(6)：85-89,5.
代谢组学在中药毒性评价中的应用
Application of Metabolomics in the Toxicity Assessment of Traditional Chinese Medicine
摘要
Abstract
To establish a reliable method for the evaluation of toxicity of traditional Chinese medicine( TCM) is one of the important issues of Chinese medicine research.However, previous evaluation methods have many limitations in explai-ning the toxic mechanisms of TCM, so it is necessary to seek new breakthroughs.In recent years,the metabolomics ap-proach, which is based on the systematic strategy, provides a new platform for illuminating the toxicity mechanisms of exogenous compounds or drugs, as its holistic concept resembles the theory of TCM.In this paper, the application of metabolomics in toxicity assessment of components, extracts and multi-herb compatibility of TCM in recent years are re-viewed, so as to provide the reference for the extensive standardization study of toxicity assessment of TCM by metabolo-mics approach.关键词
中药/毒性/代谢组学Key words
Traditional Chinese medicine/Toxicity/Metabolomics分类
医药卫生引用本文复制引用
王卓,张青山,毛茜,刘丽芳,李松林..代谢组学在中药毒性评价中的应用[J].中医药学报,2014,(6):85-89,5.基金项目
国家自然科学基金（No．81160541，81373946）；江西省卫生厅中医药科研项目 （）
