井冈山大学学报（自然科学版）Issue(4)：70-74,5.DOI:10.3969/j.issn.1674-8085.2015.04.013
爵床煎剂对小鼠镇痛抗炎作用初探
PRELIMINARY STUDY ON THE ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OFROSTELLULARIA PROCUMBENS DECOCTION IN MICE
摘要
Abstract
Objective:To investigate the analgesic and anti-inflammatory effects ofRostellularia procumbens in mice. Methods:Byusing the hot-plate and acetic acid writhing method to induce pain in mice, and observe the analgesic effect of different doses ofR. procumbensdecoction. Byusing the ear tumefaction, foot swelling to induce inflammation in mice, and observe the anti-inflammatory effect of different decoction doses.Results: Different doses ofR. procumbensdecoction could significantly elevate the pain threshold with hot plate method (P < 0.01), comparing with the saline control group. High, medium decoction dosesandlow-dose for 15, 30, 60 min could significantly elevate the pain threshold with hot plate method (P < 0.01), comparing with the self-administration earlier. Compared with the saline control group, the decoction could significantly reduce the number with acetic acid writhing method, restrain mouse ear tumefaction caused by xylene and mouse foot swelling caused by egg white (P < 0.01).Conclusion:The results showsR. procumbens decoction has the analgesic effects and anti-inflammatory.关键词
爵床/水煎剂/镇痛/抗炎Key words
Rostellularia procumbens/decoction/analgesia/anti-inflammation分类
医药卫生引用本文复制引用
刘兵,郑丽娟,梁生林..爵床煎剂对小鼠镇痛抗炎作用初探[J].井冈山大学学报（自然科学版）,2015,(4):70-74,5.基金项目
国家科技支撑计划项目子课题项目(2012BAC11B02-6)；吉安市科技支撑计划项目(吉市科计字[2014]4号) （2012BAC11B02-6）
