摘要
Abstract
Objective To investigate the efficacy of subgingival Chlorhexidine rinse aiding periodontal basic treatment in patients of coronary artery disease with periodontitis and its effect on serum IL-10 and TNF-α levels. Methods 62 cases of stable coronary artery disease with moderate to severe chronic periodontitis patients were collected,all patients were given base periodontal treatment,including subgingival scaling therapy,oral health guidance,curettage and root planing subgingival,and were given subgingival Chlorhexidine rinse under adjuvant therapy at the same time.The probe depth,periodontal attachment loss,sulcus bleeding index,IL-10,TNF-αlevels of patients were compared before and after the treatment. Results The probe depth,sulcus bleeding index and periodontal attachment loss of patient after treatment were lower than prior treatment.The differences were statistically significant (P<0.05).IL-10 level was higher than prior treatment.TNF-αlevel was lower than prior treatment,the differences were statistically significant (P<0.05). Conclusion Subgingival Chlorhexidine rinse aiding periodontal basic treatment in patients of coronary artery disease with periodon-titis can significantly improve periodontal index,elevate IL-10 levels,lower TNF-αlevel,and is conducive to the preven-tion,treatment and delaying of coronary heart disease.关键词
冠心病/牙周炎/氯己定/IL-10/TNF-αKey words
Coronary heart disease/Periodontitis/Chlorhexidine/IL-10/TNF-α分类
医药卫生
