中国当代医药Issue(21):67-69,72,4.
黄葵胶囊联合ACEI及ARB治疗早期糖尿病肾病的临床效果
Clinical effects of Abelmoschus moschatus capsule combined with ACEI and ARB on early stage of diabetic nephropathy
摘要
Abstract
Objective To observe the efficacy and safety of Abelmoschus moschatus capsule combined with ACEI and ARB on the urinary albumin excretion rate of early stage diabetic nephropathy (DN). Methods 60 patients with early stage DN were randomly divided into two groups,with 30 cases in each group.Based on treatment of controlling blood glucose,the control group was given enalapril and irbesartan,the observation group was given Abelmoschus moschatus capsule based on the treatment of control group.The urinary protein excretion rate(UAER)of 24 h,serum creatinine(SCr), blood urea nitrogen(BUN) and blood glucose,blood pressure,and adverse reactions between two groups was observed re-spectively after treatment. Results With the treatment time prolonged,UAER,SCr and BUN of observation group was lower than that of control group respectively,with statistical difference (P<0.05).The blood glucose and blood pressure of observation group was lower than that of control group respectively,with statistical difference(P<0.05).There were 2 cas-es in observation group,no case in control group with adverse reactions,with no statistical differenc between two groups (P>0.05). Conclusion Abelmoschus moschatus capsule combined with ACEI and ARB in the treatment of early stage diabetic nephropathy is a safe,effective treatment scheme.关键词
黄葵胶囊/血管紧张素转化酶抑制剂/血管紧张素域受体拮抗剂/糖尿病肾病Key words
Abelmoschus moschatus Capsule/Angiotensin converting enzyme inhibitors/Angiotensin II receptor an-tagonist/Diabetic nephropathy分类
医药卫生引用本文复制引用
欧玉玲,罗维俭,陈勇..黄葵胶囊联合ACEI及ARB治疗早期糖尿病肾病的临床效果[J].中国当代医药,2015,(21):67-69,72,4.基金项目
广东省云浮市科技计划项目 ()