临床口腔医学杂志Issue(8)：469-472,4.DOI:10.3969/j.issn.1003-1634.2015.08.007
白色念珠菌感染对口腔白斑中RIP2和Caspase－12表达的影响
Effects of Candidal albicans infection on expression of RIP2 and Caspase-12 in oral leukoplakia
摘要
Abstract
Objective:The objective of the study was to investigate the differential expression of RIP2 and Caspase-12 in oral leukoplakia with or without Candida albicans infection. Method:Hematoxylin-eosin staining,silver staining and immunohistochemical staining were adopted to determine Candida albicans infection in 40 different cases of oral leukoplaki-a. Immunohistochemistry was used to investigate the expression of RIP2 or Caspase-12 in oral leukoplakia with or without Candida albicans infection. Then Image J software was employed to analyze the main optical density of immunohistochemical images,which represented the levels of RIP2 or Caspase-12. Result:The levels of RIP2 and Caspase-12 expressed in can-dida albicans leukoplakia were both higher than those in leukoplakia without candida albicans infection(P<0.05). Conclu-sion:Candida albicans infection may induce the expression of RIP2 and Caspase-12 in oral leukoplakia.关键词
白色念珠菌/口腔白斑/受体相互作用蛋白2/Caspase-12Key words
Candida albicans/oral leukoplakia/RIP2/Caspase-12分类
医药卫生引用本文复制引用
蒋文晖,王文梅,王翔,钱雅洁,高雅凡,段宁,蒋红柳,白杨..白色念珠菌感染对口腔白斑中RIP2和Caspase－12表达的影响[J].临床口腔医学杂志,2015,(8):469-472,4.基金项目
国家自然科学基金项目（81070839）江苏省临床医学科技专项（BL2014018）南京市科技计划项目 （）
