外科理论与实践Issue(4)：333-337,5.DOI:10.16139/j.1007-9610.2015.04.013
围手术期输血对胃癌病人预后的影响
Association of perioperative blood transfusion and prognosis of patients with gastric cancer
摘要
Abstract
Objective To investigate the association of perioperative blood transfusion including concentrated suspen-sions of erythrocytes with the prognosis of gastric cancer patients. Methods Clinical data were collected retrospectively with 281 consecutive patients who had curative gastric resection at Division of Gastric Cancer Department of Surgery Rui-jin Hospital between 2008 to 2009. The effect of blood transfusion on patient survival was evaluated. Results Five-year overall survival of 281 gastric cancer patients was 64.8%(182/281). The patients in perioperative blood transfusion group experienced a significantly lower 5-year survival when compared with those in non-transfusion group (45.8%vs. 72.7%, P<0.001). Multivariate analysis suggested blood transfusion was an independent prognostic factor on long-term survival of gastric cancer patients (P=0.004, HR=1.935, 95%CI: 1.183-2.672). Five-year survival of blood transfusion preoperative, intraoperative, and postoperative was 60%(15/25), 33.3%(14/42), and 56.3%(9/16), respectively. There was no significant difference in 5-year survival of gastric cancer patients with different amounts of blood transfused statistically (P>0.05). Conclusions Perioperative blood transfusion including concentrated suspensions of erythrocytes was an independent prog-nostic factor of gastric cancer patients despite no diffenence of the amount transfused. Perioperative blood transfusion should be avoided on gastric cancer patients whenever possible especially intraoperative blood transfusion.关键词
胃癌/围手术期输血/预后Key words
Gastric cancer/Perioperative blood transfusion/Prognosis分类
医药卫生引用本文复制引用
王仁佐,燕敏,严超,刘文韬,朱正伦,陈明敏,刘炳亚,朱正纲..围手术期输血对胃癌病人预后的影响[J].外科理论与实践,2015,(4):333-337,5.基金项目
上海交通大学医学院基金 （）
