中国组织工程研究Issue(31)：5072-5078,7.DOI:10.3969/j.issn.2095-4344.2015.31.028
弹性髓内钉与外固定架修复儿童股骨干骨折的Meta分析
Meta-analysis of flexible intramedullary nailing and external fixation for pediatric femoral shaft fractures
摘要
Abstract
BACKGROUND:Flexible intramedulary nailing and external fixation for pediatric femoral shaft fractures are two common methods in the clinic. It remains controversial which fixation methods are better. OBJECTIVE:To systematicaly evaluate the therapeutic effects of flexible intramedulary nailing and external fixation for pediatric femoral shaft fractures. METHODS: A computer-based search was performed on PubMed, Embase, Medline, and Cochrane library for literatures on clinical controled trials of flexible intramedulary nailing and external fixation for pediatric femoral shaft fractures published before November 25, 2014. Literature language was not limited. The age of subjects was from 3 to 15 years. Modified Jadad was utilized to assess methodological quality of the included studies. Meta-analysis was carried out using Stata 12.0 software. RESULTS AND CONCLUSION:Six papers involving 237 patients were included. Meta-analysis results showed that compared with external fixation, a low incidence of overal complications [relative risk (RR)=0.30, 95% confidence interval (CI): 0.19-0.46;P < 0.001] and pin-hole infection (RR=0.286, 95%CI: 0.13-0.61;P= 0.001), but a high risk of needle tail irritation (RR=1.86, 95%CI: 1.35-2.56;P < 0.001) were found folowing flexible intramedulary nailing. No significant differences in other complications were found between the two groups. These results confirm that compared with external fixation, elastic intramedulary nail has fewer complications and faster fracture healing. Elastic intramedulary nail is recommended for single pediatric femoral shaft fractures. However, external fixation is a better option for high energy injury of lower limbs, multiple trauma or severely soft tissue injury.关键词
植入物/骨植入物/儿童股骨干骨折/疗效/弹性髓内钉/外固定架/固定/针道感染/总体并发症/针尾激惹/Meta 分析Key words
Femur/Fractures, Bone/Bone Nails/Postoperative Complications/Meta-Analysis/Evidence-Based Medicine分类
医药卫生引用本文复制引用
郭永成,邢光卫,夏冰,冯国明,董延召,牛学强,何谦益..弹性髓内钉与外固定架修复儿童股骨干骨折的Meta分析[J].中国组织工程研究,2015,(31):5072-5078,7.基金项目
郑州市科技计划项目(131PPTGG409-25)Funding:the Zhengzhou Science and Technology Project, No.131PPTGG409-25 （131PPTGG409-25）
