陈小瑜 1杨艾 1李婷 2杨茗 1刘关键 1吴红梅1
作者信息
- 1. 610041 四川省成都市，四川大学华西医院老年医学中心
- 2. 610041 四川省成都市，四川大学华西医院循证医学与临床流行病学中心
- 折叠
摘要
Abstract
Objective To systematically review the influencing factors for type 2 diabetic kidney disease ( DKD) . Methods We made computer -based retrieval from MEDLINE (1960.01—2012.12), EMBase (1980.01—2012.12), CBM ( 1969.01—2012.12 ) , CNKI ( 1981.01—2012.12 ) , VIP ( 1989.01—2012.12 ) and Wanfang database ( 1998.01—2012.12) .RevMan 5.2 statistic software was used to conduct meta -analysis and investigate the influencing factors for type 2 diabetic kidney disease.Results We included 7 pieces of literature , among which 6 pieces were of cross -sectional study and one case was of case -control study.There were all together 3 548 subjects involved in the study .The results showed by the meta-analysis were as follows.(1) The univariate analyses of case -control study showed that age had influence on the occurrence of type 2 diabetic kidney disease , with a combining MD value of 2.37 〔95%CI (0.20, 4.54)〕; the univariate analyses of cross-sectional study showed that age had influence on the occurrence of type 2 diabetic kidney disease , with a combining MD value of 5.61 〔95%CI (1.54, 9.68)〕 .The multivariate analyses of cross -sectional research showed that age had influence on the occurrence of type 2 diabetic kidney disease , with a combining MD value of 1.02 〔95%CI (1.01, 1.03)〕 .(2) The univariate analyses of cross -sectional study showed that gender had influence on type 2 diabetic kidney disease , with a combining OR value of 1.28 〔95%CI ( 1.03, 1.58 )〕 .The multivariate analyses of cross -sectional research showed that gender had influence on type 2 diabetic kidney disease , with a combining OR value of 0.46 〔95%CI (0.22, 0.95)〕 .(3) The univariate analyses of case -control study showed that education level , marital status and the total income of a household had no influence on type 2 diabetic kidney disease , with combining OR values of 0.54 〔95%CI (0.24, 1.24)〕, 1.77 〔95%CI (0.92, 3.41)〕 and 0.74 〔95%CI (0.44, 1.24)〕 respectively.(4) The univariate analyses of case -control study showed that self-efficacy ( high level/low level ) and self -efficacy of symptom management ( high level/low level ) had influence on type 2 diabetic kidney disease , with combining OR values of 0.24 〔95%CI ( 0.10, 0.60 )〕 and 0.29 〔95%CI ( 0.10, 0.83)〕; multivariate analyses showed that self -efficacy ( high level/low level ) and self -efficacy ( intermediate level/low level) had influence on type 2 diabetic kidney disease , with combining OR values of 0.30 〔95%CI (0.11, 0.87)〕 and 0.18〔95%CI (0.06, 0.52)〕 respectively.Gonclusion Age, gender and self -efficacy are influencing factors for the occurrence of type 2 diabetic kidney disease .关键词
糖尿病,2型/糖尿病肾病/影响因素分析/Meta分析Key words
Diabetes mellitus , type 2/Diabetic nephropathies/Root cause analysis/Meta-analysis分类
医药卫生
