中国全科医学Issue(23)：2851-2855,2856,6.DOI:10.3969/j.issn.1007-9572.2015.23.025
2008-2013年江苏省甲型肝炎疫苗疑似预防接种异常反应监测分析
2008 to 2013
高君 1张晋琳 1马福宝1
作者信息
- 1. 210009江苏省南京市，江苏省疾病预防控制中心
- 折叠
摘要
Abstract
Objective To analyze the epidemiological features of adverse events following immunization ( AEFI ) of hepatitis A vaccine ( HepA) in Jiangsu Province and to evaluate the safety of the inoculation of HepA .Methods The HepA AEFI data and HepA inoculation data of Jiangsu Province from 2008 to 2013 were collected through the AEFI information system and the Information System of the Expanded Programme on Immunization of Jiangsu Province .Descriptive epidemiology method was used to analyze relevant indicators .Results A total of 2 585 HepA AEFI cases were reported during the period , including 1 068 HepA-L AEFI cases and 1 517 HepA-I AEFI cases, and the annual average incidence was 310.0/106 and 358.8/106 respectively.For adverse events of HepA -L, the reporting rate of common adverse events was 267.0/106 (920), the reporting rate of rare adverse events was 39.5/106 (136).For adverse events of HepA -I, the reporting rate of common adverse events was 334.2/106 (1 413), the reporting rate of rare adverse events was 24.1/106 (102).People aged 1 year old accounted for 83.1% among HepA -L AEFI cases; people aged 1 years old and 2 to 3 years old accounted for 57.7% and 38.7%respectively among HepA -I AEFI cases.The male-to-female ratio was 1.4∶1 among both HepA-L and HepA-I AEFI cases.And both HepA-L and HepA-I AEFI cases were reported in each season , but the proportion was slightly higher in spring and summer, accounted for 59.6% and 61.6% respectively.The main symptoms of common adverse events were fever, red and swelling and indurations; the main diagnoses of rare vaccine reactions were anaphylactic rashes .Most adverse events happened within 1d after vaccination .Conclusion HepA-L and HepA-I have good immunization safety .Fever, red and swelling, indurations and anaphylactic rash are the predominant diagnosrs following immunization and most adverse events happen within 1d after vaccination.However, the surveillance should still focus on the anaphylactoid reactions after HepA -L immunization in future .关键词
甲型肝炎疫苗/大规模疫苗接种/疑似预防接种异常反应Key words
Hepatitis A vaccines/Mass vaccination/Adverse events following immunization分类
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高君,张晋琳,马福宝..2008-2013年江苏省甲型肝炎疫苗疑似预防接种异常反应监测分析[J].中国全科医学,2015,(23):2851-2855,2856,6.
