中国药物评价Issue(3):159-161,3.
钴-60辐照对补骨脂药材指纹图谱的影响
Influence of 60 Co-γIrradiation on Fingerprint of Psoralea Corylifolia
黄晓婧 1周晓英 1周世玉1
作者信息
- 1. 成都市食品药品检验研究院,四川成都610045
- 折叠
摘要
Abstract
Objective:Establish the fingerprint of psoralea corylifolia by high performance liquid chromatography(HPLC), to study the influence of different doses 60 Co-γirradiation on the effective components.Methods:Carring out the method for HPLC.We use Shim-Pack VP-ODS(4.6 mm ×250 mm,5 μm) column as detached dowel and a mixture of acetonitrile and water as mobile phase for gradient elution, the detection wavelength was set at 246 nm.Results:Fingerprint was established with 8 common peaks, the similarity was in the range of 0.999~1.000, and methodology reached the required standard.Conclusion:The effective ingredients of fructus psoralea had no obvious change before and after 60 Co-γirradiation with different doses.关键词
钴-60射线/补骨脂/指纹图谱Key words
60 Co-γirradiation/Psoralea corylifolia/Fingerprint分类
医药卫生引用本文复制引用
黄晓婧,周晓英,周世玉..钴-60辐照对补骨脂药材指纹图谱的影响[J].中国药物评价,2015,(3):159-161,3.