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明眸滴丸制备工艺研究

张丽军 董明芝

中国药业Issue(15):17-18,19,3.
中国药业Issue(15):17-18,19,3.

明眸滴丸制备工艺研究

Study on The Forming Process of Mingmou Dropping Pills

张丽军 1董明芝2

作者信息

  • 1. 陕西中药研究所咸阳市滴丸制剂工程技术研究中心,陕西 咸阳 712000
  • 2. 西安正大制药有限公司,陕西 西安 710043
  • 折叠

摘要

Abstract

Objective To optimize the forming process of Mingmou dropping pills through experimental study. Methods The method is us-ing orthogonal test to achieve the best preparation process of dropping pills. The detection parameters include the weight coefficient of vari-ation, time limit of dissolution, and hardness of dropping pills. Results The optimal preparation process of dropping pills includes: the ma-trix of dropping pills is PEG6000; the ratio of drug and matrix is 1 : 1. 5; and the coolant temperature is 8℃. Conclusion The preparation technology of Mingmou dropping pills is simple, feasible, reasonable and stable; the scoring index is also objective, reliable and reasonable.

关键词

明眸滴丸/制备工艺/正交试验

Key words

Mingmou dropping pills/preparation process/orthogonal test

分类

化学化工

引用本文复制引用

张丽军,董明芝..明眸滴丸制备工艺研究[J].中国药业,2015,(15):17-18,19,3.

基金项目

陕西省“13115”科技创新工程重大科技专项项目,项目编号2009ZDKG -88。 ()

中国药业

1006-4931

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