中国药业Issue(15)：145-145,146,2.
拉莫三嗪添加－替换疗法治疗小儿难治性癫痫100例
Lamotrigine Added - Replacement Therapy in the Treatment of Pediatric Epilepsy Valproate Invalid
蔡少华 1林茂增1
作者信息
- 1. 中国人民解放军第 175 医院儿科，福建 漳州 363000
- 折叠
摘要
Abstract
Objective To observe the curative effect of lamotrigine added - replacement therapy of refractory epilepsy in children. Methods Selected 100 cases of refractory epilepsy in our hospital in recent years and divided into big attack group, complex group, simple group, small attack group underwent lamotrigine added - replacement therapy. Evaluated the effect of drugs according to the onset times and improve the situation of children with a monthly average of epilepsy. Results The overall clinical efficacy in children com-pared with various types of epilepsy, treatment was found the highest efficiency was a small attack group, the second group was com-plex, and the big attack group and single group were low. 3 months after treatment, treatment after the onset times of 6 months com-pared with before treatment were significantly decreased, the difference changes significantly. Conclusion For The invalid application of valproic acid in children with refractory epilepsy, lamotrigine added - replacement therapy can reduce the occurrence of adverse reaction, better in the foundation to enhance the original treatment effect on the protection of the nervous system function, prognosis is good, it is recommended for clinical application.关键词
拉莫三嗪/丙戊酸/小儿癫痫/疗效Key words
lamotrigine/valproic acid/epilepsy/effect分类
医药卫生引用本文复制引用
蔡少华,林茂增..拉莫三嗪添加－替换疗法治疗小儿难治性癫痫100例[J].中国药业,2015,(15):145-145,146,2.
