波谱学杂志Issue(3)：450-461,12.DOI:10.11938/cjmr20150306
三维多回波流动补偿定量磁化率成像（QSM）方法研究
Three-Dimensional Multi-Echo Quantitative Susceptibility Mapping with Flow Compensation
摘要
Abstract
Venous blood oxygen saturation, cerebral microbleeds, iron deposition and tissue calcification can be measured by quantitative susceptibility mapping (QSM) via deconvolving the magnetic resonance (MR) phase signal. However, accurate estimation of phase signal and magnitude image in QSM may be affected by flow-induced errors in the presence of field gradient, which would ultimately lead to errors in the quantitative susceptibility map reconstructed. The aim of this study is to develop a method for correcting the flow-induced errors in phase signal and magnitude image in QSM. Flow-compensated data acquisition was achieved using a three-dimensional full flow compensated multi-echo gradient echo sequence. Phantom andin vivo experiments were carried out to validate the method proposed. The results of these experiments demonstrated that flow compensation can reduce errors in the phase signal and magnitude images. Improved quantitative susceptibility map of the superior sagittal sinus vein in human brain could be obtained with the proposed method.关键词
磁共振成像(MRI)/定量磁化率成像(QSM)/流动补偿/三维多回波梯度回波/流动伪影Key words
MRI/quantitative susceptibility mapping/flow compensation/3D multi-echo GRE/flow artifacts分类
数理科学引用本文复制引用
翁鹏飞,董芳,王前锋,裴孟超,刘田,王乙,李建奇..三维多回波流动补偿定量磁化率成像（QSM）方法研究[J].波谱学杂志,2015,(3):450-461,12.基金项目
国家自然科学基金资助项目(81271533) （81271533）
