滨州医学院学报Issue(4)：257-259,3.
继发性甲状旁腺功能亢进患者甲状旁腺切除术后重度低钙血症相关因素分析
Analysis of factors associated with severe hypocalcemia after parathyroidectomy for secondary hyperparathyroidism patients
艾向南 1金昌国 1欧阳才国 1孙鹏超 1胡浩1
作者信息
- 1. 航天中心医院肝胆外科 北京 100049
- 折叠
摘要
Abstract
Objective To explore the factors associated with severe hypocalcemia(SHC) after parathyroidectomy for seconda‐ry hyperparathyroidism(SHPT) patients ,and to establish a strategy for the prevention and treatment of SHC .Methods A ret‐rospective study of clinical data was conducted in the cases of SHPT undergone parathyroidectomy in our hospital from Mar 2012 to May 2014 .Uni‐and multivariate analysis was conducted to define independent influence factors for the SHC ,and the cut‐off values of quantitative factors were defined .Results Eighty‐eight cases of clinical data were collected and the SHC was shown in 46 cases(52.3% ) after operation .Univariate analysis showed that age ,ALP ,iPTH and the resected parathyroid gland number(RTPN)emerged statistically significant difference ,and multivariate analysis showed that age ,iPTH and RTPN ≥4 were the independent influence factors for the SHC individually .The defined cut‐off values of age and iPTH were 48y (PPV68.8% ,NPV67.5% )and 1 750 pg/ml(PPV85.4% ,NPV87.5% ) ,respectively .Conclusion Age ,PT H level and the RT‐PN are the independent influence factors for the SHC after parathyroidectomy in SHPT patients .Selective intravenous supple‐mentation of calcium for the patients at high risk and selection of reasonable surgical manner can be established as preparatory strategy for the prevention and treatment of the SHC .关键词
慢性肾衰/甲状旁腺功能亢进/甲状旁腺切除/低钙血症Key words
chronic renal failure/hyperparathyroidism/parathyroidectomy/hypocalcemia分类
医药卫生引用本文复制引用
艾向南,金昌国,欧阳才国,孙鹏超,胡浩..继发性甲状旁腺功能亢进患者甲状旁腺切除术后重度低钙血症相关因素分析[J].滨州医学院学报,2015,(4):257-259,3.
