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3.0T DCE-MRI定量分析在前列腺癌与增生鉴别诊断中的应用价值

徐嬿 冷晓明 郑芸 赵曼 曾道辉 韩晓蕊 冯欣 王晓春

磁共振成像Issue(8):608-612,5.
磁共振成像Issue(8):608-612,5.DOI:10.3969/j.issn.1674-8034.2015.08.010

3.0T DCE-MRI定量分析在前列腺癌与增生鉴别诊断中的应用价值

Quantitative diagnostic value of 3.0 T dynamic contrast-enhanced MRI in different diagnosis of prostate cancer and hyperplasia

徐嬿 1冷晓明 1郑芸 1赵曼 1曾道辉 1韩晓蕊 1冯欣 1王晓春1

作者信息

  • 1. 广州中医药大学第一附属医院影像科,广州 510405
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摘要

Abstract

AbstractObjective:To explore the diagnostic value of quantitative analysis parameters of DCE-MRI in prostate cancer diagnosis, and to evaluate the correlation between Ktrans, Kep and Ve and Gleason scores. Materials and Methods:Forty-three prostate diseases patients pathologically proved underwent conventional MRI and DCE-MRI examinations, including 27 patients with prostate cancer and 16 with prostate hyperplasia. The variations of the value of Ktrans, Kep and Ve between the prostate cancer and hyperplastic tissues were measured and compared, and the correlations between Ktrans, Kep and Ve and Gleason scores were studied.Results:The Ktrans, Kep and Ve values of cancerous area were (0.312±0.085) min-1, (0.818±0.098) min-1 and (0.379±0.031), while, for hyperplastic area were (0.213±0.046) min-1, (0.537±0.076) min-1 and (0.324±0.034). The values of Ktrans, Kep, Ve were signiifcantly higher in prostate cancer than in hyperplastic tissues; and Ktrans, Kep, Ve values were not relevant with Gleason score.Conclusion:DCE-MRI quantitative analysis plays a signiifcant role in prostate cancer diagnosis, and may help in differential diagnosis of prostate tumors. Ktrans, Kep and Ve values were not relevant with Gleason score.

关键词

前列腺肿瘤/前列腺增生/动态增强/磁共振成像

Key words

Prostate neoplasms/Benign prostatic hyperplasia/Dynamic contrast-enhanced/Magnetic resonance imaging

分类

医药卫生

引用本文复制引用

徐嬿,冷晓明,郑芸,赵曼,曾道辉,韩晓蕊,冯欣,王晓春..3.0T DCE-MRI定量分析在前列腺癌与增生鉴别诊断中的应用价值[J].磁共振成像,2015,(8):608-612,5.

磁共振成像

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1674-8034

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