重庆医学Issue(24):3348-3349,2.DOI:10.3969/j.issn.1671-8348.2015.24.012
降脂通络软胶囊联合瑞舒伐他汀对2型糖尿病合并高脂血症患者效果观察∗
Effects of Jiang Zhi Tong Luo Soft Capsule and rosuvastatin on type 2 diabetes combined with hyperlipidemia
摘要
Abstract
Objective To observe the effect of combined administration of Jiang Zhi Tong Luo Soft Capsule(JTSC)and rosu-vastatin on type 2 diabetic with hyperlipemia and its possible mechanisms.Methods Eighty cases of Type 2 diabetic patients with hyperlipemia were divided into combine treatment group (40 cases)and control group (40 cases ).On the basis of routine treat-ment,patients in the combine treatment group were treated by oral 10 mg rosuvastatin (once a day)and oral 100 mg JTSC (three times a day ).Patients in control group were treated by oral 10 mg rosuvastatin (once a day and continuously for 12 weeks).We de-tected the liver function,renal functions,creatine kinase,TC,TG,LDL,HDL and hs-CRP were tested before and after treatments. Results After 12 weeks treatment,the combine treatment group was much better than the control group in reducing the level of TG,TC,LDL,hs-CRP and increasing HDL-C(P <0.05 ).Conclusion Rosuvastatin can effectively treat Type 2 diabetic patients with hyperlipemia.Combined administration of JTSC and rosuvastatin shows better effect than rosuvastatin used alone on the treat-ment of Type 2 diabetic patients with hyperlipemia.关键词
糖尿病,2 型/高脂血症/降脂通络软胶囊/瑞舒伐他汀Key words
diabetes mellitus,type2/hyperlipidemia/Jiang Zhi Tong Luo Soft Capsule(JTSC)/rosuvastatin分类
医药卫生引用本文复制引用
郭慧,刘良专,刘江华..降脂通络软胶囊联合瑞舒伐他汀对2型糖尿病合并高脂血症患者效果观察∗[J].重庆医学,2015,(24):3348-3349,2.基金项目
湖南省衡阳市社会发展科技支撑计划(2013KJ69)。 (2013KJ69)