摘要
Abstract
Objective: To s tudy the role of the monitoring technology of PiCCO in early goal-directed therapy (EGDT) on the old patients with ARDS and septic shock. Methods:68 patients with ARDS and septic shock admitted since May 2013 were randomized into 2 groups, 38 cases in the treatment group with PiCCO monitoring indicators for guiding fluid resuscitation and 30 cases in the control group with conventional fluid resuscitation indicators. Then we recorded the results on three time points, 6h, 12h, 24h in these two groups in which MAP, CVP, ScvO2, PaO2/FiO2 and the dosage of the vasoactive substances after 24h were analyzed. At last, we analyze patients’ health standard rate in 6h, 12h, 24h, and the death rate after 4 weeks. Results:The fluid resuscitation showed significant differences in these two groups in 6h、12h、24h(t=3.102, 3.296, 2.853, P<0.05). In the treatment group, the dosage of the vasoactive substances after 24h was significantly lower than that of the control group(t=1.895,4.216,P<0.05), the MAP, CVP, ScvO2, PaO2/FiO2 were significantly higher in the treatment group(P<0.05). There was a significant difference in 24h patient’s health standard rate and the death rate after 4 weeks (χ2=11.250,7.071,P<0.05). Conclusion: Application of PiCCO monitoring technology on EGDT in guidance of fluid resuscitation in the old patients with ARDS and septic shock is of great importance, which is worth of promoting.关键词
PiCCO/ARDS合并感染性休克/EGDTKey words
PiCCO/ARDS and septic shock/EGDT