中医学报Issue(8):1085-1088,4.DOI:10.16368/j.issn.1674-8999.2015.08.375
晚期非小细胞肺癌中医证候分布及动态演变临床研究
Clinical Study of the Distribution and Dynamic Evolution of Traditional Chinese Medicine Syndromes for Advanced Non-Small-Cell Lung Cancer
摘要
Abstract
Objective:To observe the distribution and dynamic evolution of traditional Chinese medicine( TCM)syndromes for advanced non-small-cell lung cancer( NSCLC). Methods:Prospective epidemiological methodology was adopted to observe the dynamic syndromes of the initial NSCLC treatment at seven different time points(before the treatment,and at 42,84,150,270,390 and 510 days after treat-ment). Results:There were a total of 20 different TCM syndroms at different time points. In terms of syndrome elements,in the patients with Qi deficiency syndrome,compare the curative effect with before and after the treatment(42 d,84 d,390 d,510 d),there was a sig-nificant difference(P﹤0. 05). in the patients with Yin deficency syndrom,phlegm-damp syndrom and syndrome of blood stasis,com-pare the curative effect with before and after the treatment(510 d),there was a significant difference(P﹤0. 05). In terms of excess and deficiency,in the patients with syndrome of intermingled deficiency and excess,compare the curative effect with before and after the treatment(42 d,84 d,390 d,510 d),The difference is statistically significant. Conclusion:With the development of advanced NSCLC, single syndrome gradually declined and multiple syndromes increased. Deficiency syndromes and excess syndromes showed adecreasing, while the syndrome of intermingled deficiency and excess increased. Qi deficiency,Yin deficiency,phlegm-damp syndrom and syndrome of blood stasis were also on the increase as disease progressed.关键词
非小细胞肺癌/证候分布/证候演变Key words
non-small-cell lung cancer/distribution of syndromes/evolution of syndromes分类
医药卫生引用本文复制引用
李丛煌,刘瑞,郑红刚,鲍艳举,秦英刚,郭秋均,侯炜,花宝金..晚期非小细胞肺癌中医证候分布及动态演变临床研究[J].中医学报,2015,(8):1085-1088,4.基金项目
国家十一五科技支撑计划资助项目 ()