中国当代医药Issue(22)：42-44,3.
盐酸替罗非班对急性心肌梗死患者冠状动脉介入治疗的效果观察
Effect observation of tirofiban hydrochloride on percutaneous coronary intervention in acute myocardial infarction patients
摘要
Abstract
Objective To explore the effect of tirofiban hydrochloride on percutaneous coronary intervention in patients with acute myocardial infarction (AMI). Methods 120 AMI patients from October 2013 to December 2014 in our hos-pital were selected and randomly divided into the control group,the experimental group one and the experimental group two.Different treatment methods was given reapectively.The clinical manifestations of re-flow of vascular blood flow be-ing invaded by infarction during PCI,detection of myocardial marker and occurrence of major adverse cardiovascular events (MACE) among three groups was compared. Results The proportion of TMPG3 and TIMI3 in the experimental group was higher than that in the control group and the experimental group one,with significant difference (P<0.05).The activity of blood platelets and the incidence rate of MACE in the experimental group two was lower than that in the control group and the experimental group one,with significant difference (P<0.05). Conclusion Tirofiban hydrochloride exerts a positive therapeutic effect in PCI,and its effect is related with the dosage.High-dose of tirofiban hydrochloride not only doesn’t take effect,but increases the risk of hemorrhage,even platelet activation.Therefore,appropriate dose of tirofiban hydrochloride can improve the clinical therapeutic effect,it is worthy of clinical promotion and application.关键词
盐酸替罗非班/急性心肌梗死/经皮冠状动脉介入治疗/围术期Key words
Tirofiban hydrochloride/Acute myocardial infarction (AMI)/Percutaneous coronary intervention (PCI)/Peri-operative period分类
医药卫生引用本文复制引用
廖富彪,张志广,廖尚宇,李晨曦,余丹青..盐酸替罗非班对急性心肌梗死患者冠状动脉介入治疗的效果观察[J].中国当代医药,2015,(22):42-44,3.基金项目
广东省云浮市医药卫生科研课题 （）
