四川精神卫生Issue(4)：358-363,6.DOI:10.11886/j.issn.1007-3256.2015.04.022
网络成瘾者在不同情绪面孔刺激下的持续注意任务事件相关电位与治疗转归的相关性
Relationship of treatment outcome with different emotion face stimulus on sustained attention activity relevant potential in patients with Internet addiction disorder
摘要
Abstract
Objective To study the characteristics of brian potential evoked by different emotion faces during sustained attention tasks in patients with internet addiction disorder(IAD)between before and after the treatment,and to analyze the correlation with treatment effect. Methods 38 patients met with the clinical diagnostic criteria for Internet addiction formulated(IAD group)before and after treatment and 38 healthy volunteers matched with sex,age and education(control group)were asked to fulfill the assignment after they were presented with 4 faces of joy,anger,sadness,fear and relative portal would been recorded. Then the N170 potentials evoked by emotion faces and P300 potentials evoked by target stimulus of the subjects were observed in the control group and IAD group before and after treatment. The Chinese Internet Addiction Scale(CIAS),Family Assessment Device(FAD),HAMD,HAMA were used to determine the internet addiction severity of tow groups and the curative efficacy of IAD group. To compare the characteristics of event related potentials between before and after treatment in IAD group,and compared with the control group,and the correlation a-nalysis were performed between them and the treatment effect(scale). Results ①The specific N170 wave amplitudes in the temporal occipital stimulated by emotion faces were smaller in patients with IAD before treatment than in the controls[e. g. fear faces,(17. 5 ± 16. 7)μv vs. (25. 8 ± 13. 4)μv,P < 0. 05]. The P300 latencies in parietal occipital stimulated by emotion faces were longer in patients with IAD before treatment than in the controls[e. g. fear faces,( 452. 6 ± 50. 3)ms vs.(426. 7 ± 28. 4)ms,P < 0. 05]. There were no significant difference in evoked N170 amplitude and latency among different emotion faces,and the smallest P300 ampli-tude and the longest P300 latency were found in patients with IAD before treatment during the sustained attention tast to the fear faces.②There were no significant difference in evoked amplitudes and latencies of N170 or P300 stimulated by 4 emotion faces in IAD group after treatment than in the controls,respectively(all P > 0. 05). ③The negative correlation was found between the evoked N170 ampli-tudes stimulated by 4 emotion faces and the scores of scales(CIAS,FAD,HAMa + d),P300 latencies was positively correlated with the scores. No correlation was found between the evoked N170 latencies ,P300 amplitudes and the scores of scales. Conclusion It suggests that patients with IAD show less reactivity to the fear stimuli which might indicate that fear faces could affect IAD patientsˊemo-tional regulation and their sustained attention. There were positive correlation between N170 amplitudes and the efficacy,negative cor-relation between P300 latencies and the efficacy in patients with IAD.关键词
网络成瘾/情绪面孔/持续注意/事件相关电位/治疗转归Key words
Internet addiction disorder(IAD)/Emotional faces/Sustained attention/Event related potentials(ERP)/Treat-ment outcome分类
医药卫生引用本文复制引用
宋来云,黄淑燕,向锋,郑小泳,肖攀攀,黄金焕,梁雪玲,李艳容,徐伏莲..网络成瘾者在不同情绪面孔刺激下的持续注意任务事件相关电位与治疗转归的相关性[J].四川精神卫生,2015,(4):358-363,6.基金项目
江门市科技计划项目 （）
