陕西中医Issue(8):1099-1100,2.DOI:10.3969/j.issn.1000-7369.2015.08.079
坤复康胶囊对慢性盆腔炎大鼠 VEGF 、NO 的影响
Effects of Kunfukang capsule on VEGF and NO of chronic pelvic inflammatory disease in rats
逯莉 1王相东2
作者信息
- 1. 陕西国际商贸学院 咸阳712046
- 2. 陕西中医药大学 咸阳 712046
- 折叠
摘要
Abstract
Objective :To investigate the Kunfukang capsule in the treatment of chronic pelvic inflammatory disease (sequelae of pelvicinflammatory disease ) effect and its mechanism .Methods :By “mixed bacterial suspension”made in rats model of chronic pelvic inflammatory disease ,and were randomly divided into blank group ,model group , Kunfukang high dose group ,Kunfukang low dose group ,Fuyankang group .The VEGF was detected by immunohisto‐chemical staining ;NO content was determined by fluorescence spectrophotometry .Results :VEGF in model group ,the content of NO were significantly higher than those in other groups (P < 0 .05) ;Kunfukang high dose group ,VEGF con‐tent and Fuyankang group compared with significant difference (P < 0 .05) ;Kunfukang high ,low dose group and NO content in Fuyankang group were significantly different (P < 0 .05) .Conclusion :Kunfukang Capsule in the treatment of chronic pelvic inflammatory disease can reduce the content of rat uterine tissue VEGF and NO ,can reduce the adhesion of pelvic tissue ,eliminate chronic pelvic inflammatory symptoms and thus play a role in the treatment .关键词
盆腔炎性疾病/中医药疗法/坤复康胶囊/一氧化氮/动物实验/大鼠Key words
Pelvic inflammatory disease/traditional Chinese medicine therapy/Kunfukang Capsule/Nitric oxide/Animal experimentation/Rats分类
医药卫生引用本文复制引用
逯莉,王相东..坤复康胶囊对慢性盆腔炎大鼠 VEGF 、NO 的影响[J].陕西中医,2015,(8):1099-1100,2.