中国组织工程研究2015，Vol.19Issue(30)：4876-4881,6.DOI:10.3969/j.issn.2095-4344.2015.30.023
不同肩袖补片特点:应用强度、降解速率及酸性降解物的调控
Different materials for rotator cuff repair augmentation: intensity, degradation rate and acidity degradation products
任士友 1江长青 2张文涛2
作者信息
- 1. 安徽医科大学北京大学深圳医院临床学院,广东省深圳市 518036
- 2. 北京大学深圳医院运动医学与康复科,广东省深圳市 518036
- 折叠
摘要
Abstract
BACKGROUND:It is unclearwhat kind of material for rotator cuff repair augmentation is the safest or most effective. OBJECTIVE:To review the basic research, clinical application and prospects of materials for rotator cuff repair augmentation. METHODS:Eligible studies were identified from electronic databases including EMbase, Medline, PubMed, OVID, Cochrane Library, Springerlink, CNKI, WanFang, and VIP. RESULTS AND CONCLUSION:There are four kinds of patches used for rotator cuff augmentation: tendon patches, non-degradable patches, extracelular matrix-based patches and degradable synthetic patches. Tendon patches have good mechanical strength, but postoperative foreign body reactions and increasing risk of infection and unable to recover the normal structure are problems to be solved. Non-degradable patches also have good mechanical strength, but the long-term safety is unclear. Extracelular matrix-based patches remain a lower mechanical strength and have a higher failure rate. Degradable synthetic patches are proposed to overcome these previous issues by combining wel-adjusted mechanical properties with biological additives and minimize risk of infection by completely absorbing in a time-dependent manner. However, migration of bioactive cels, regulation of degradation rate and suppression of acidic degradation products is are existing problems to be solved.关键词
生物材料/材料相容性/肩袖补片/肌腱补片/不可降解补片/细胞外基质补片/可降解补片/肩袖损伤分类
医药卫生引用本文复制引用
任士友,江长青,张文涛..不同肩袖补片特点:应用强度、降解速率及酸性降解物的调控[J].中国组织工程研究,2015,19(30):4876-4881,6.
