疑难病杂志Issue(9)：895-897,909,4.DOI:10.3969/j.issn.1671-6450.2015.09.005
芪苈强心胶囊治疗老年收缩性心力衰竭的临床疗效观察
Observation of clinical effect of Qiliqiangxin capsule on elderly patients with systolic heart failure
摘要
Abstract
Objective To observe the therapeutic effect of Qiliqiangxin capsule in the treatment of senile congestive heart failure .Methods Selected 196 cases of age more than or equal 65 elderly patients with systolic heart failure , they were randomly divided to observation group (116 cases) and control group (80 cases).Control group was given conventional diu-retics, angiotensin angiotensin converting enzyme inhibitor (ACEI) or vascular angiotensin II receptor blocker (ARB), and beta blockers, digitalis and nitric acid ester drug treatment .The observation group also added Qiliqiangxin capsule treatment, at the beginning and after 8 weeks treatment , liver function , renal function , myocardial enzyme , clinical curative effect , 6 mi-nutes walking test (6MWT), left ventricular shoot ejection fraction (LVEF), left ventricular diastolic end diastolic diameter (LVEDD), serum N-terminal pro brain natriuretic peptide precursor (NT-proBNP) changes were detected.Results Obser-vation group’s total efficiency was superior to the conventional treatment group (92.2%vs.83.85,χ2 =6.852, P <0.05);2 groups’ LVEF, NT-proBNP were improved than before treatment ( t =4.431, t =51.213, t =6.132, t =71.663, P <0.05), observation group’s NT-proBNP levels were decreased more significantly than control group ( P <0.05).The hepatic function , renal function , myocardial enzymes in two groups before and after the treatment ’ s difference had no statistical signif-icance ( P >0.05).Conclusion Qiliqiangxin capsule effectively improves the clinical symptoms and heart function in eld-erly patients with systolic heart failure , no drug adverse events , worthy of clinical application .关键词
芪苈强心胶囊/收缩性心力衰竭/脑钠肽/老年Key words
Qiliqiangxin capsule/Congestive heart failure/Brain natriuretic peptide/Elderly引用本文复制引用
李争,钱玉红,周静,王敏,范志媛,张淋淋,梁凤兰,史俊玲..芪苈强心胶囊治疗老年收缩性心力衰竭的临床疗效观察[J].疑难病杂志,2015,(9):895-897,909,4.基金项目
河北省唐山市科技计划项目 （）
