摘要
Abstract
Objective To investigate the influence of Shenmai injection on electrocardiogram ( ECG ) changes in patients with coronary heart disease( CHD)of different TCM syndromes. Methods Enrolled 402 CHD inpatients who received Shenmai injection in Beijing Ditan Hospital Affiliated to Capital Medical University from January 2011 to February 2015 and assigned them into TCM group. According to TCM syndrome differentiation,the TCM group was further divided into blood stasis group(n=76),phlegm stasis group(n=104),Qi and Yin deficiency group(n=112)and heart-kidney Yin deficiency group(n =110). Another 96 CHD patients were enrolled as control group,in which only western medicine treatment was conducted during the same period. Both groups were given basic treatments, including conventional restriction on salt consumption,rest,cardiotonic drug,oxygen uptake,vascular dilation and diuresis. The TCM group was also given Shenmai injection(50 ml,intravenous drip,once per day). ECG index of incidence of PTF-V1≤-0. 04 mm·s,abnormity in ST segment,ischemic T wave,atrioventricular block,QTcd and JTcd were compared among the five groups. Results Before treatment,the five groups were not significantly different(P>0. 05)in incidence of PTF-V1≤-0. 04 mm·s,abnormity in ST segment, ischemic T wave, atrioventricular block, QTcmax, QTcmin, QTcd, JTcmax, JTcmin and JTcd. After treatment,the Qi and Yin deficiency group was lower(P<0. 005)than the control group in PTF-V1≤-0. 04 mm·s and the incidence of atrioventricular block;the Qi and Yin deficiency group was lower ( P<0. 05 )in QTcd and JTcd than the control group,the blood stasis group,the phlegm stasis group and the heart -kidney Yin deficiency group. Conclusion Shenmai injection has a positive effect on the improvement of ECG of CHD patients. The ECG improvement of CHD patients with Qi and Yin deficiency is more significant.关键词
冠心病/心电描记术/参麦注射液/辨证分型Key words
Coronary disease/Electrocardiography/Shenmai injection/Syndrome differ classification分类
医药卫生
