中国全科医学Issue(21)：2564-2567,2572,5.DOI:10.3969/j.issn.1007-9572.2015.21.015
肺癌化疗患者癌因性失眠及肿瘤相关症状调查研究
Relationship Between Cancer-related Insomnia and Relevant Symptoms of Tumor in Patients With Lung Cancer During Chemotherapy
摘要
Abstract
Objective To investigate the status of cancer -related insomnia ( CRI ) in patients with lung cancer during chemotherapy and its relationship with relevant symptoms of tumor.Methods Using convenience sampling method, the study enrolled 180 inpatients with lung cancer from the Oncology Department and the Radiotherapy Department of Tumor Hospital of Tianjin Medical Hospital from February to September 2014.Questionnaire survey was conducted with the patients.A total of 155 questionnaires were collected, with an effective returning rate of 86.1%.The questionnaire survey included a questionnaire of general data, the Pittsburgh sleep quality index ( PSQI) questionnaire and the MD Anderson symptom inventory-lung cancer (MDASI-L) questionnaire.According to PSQI score, the patients were divided into CRI group (PSQI>7) and normal group ( PSQI≤7) .Comparison was conducted between the patients and national norms in the scores of PSQI factors ( including sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleeping disturbance, use of sleeping medication, daytime dysfunction) and PSQI score; the correlation between PSQI score and each MDASI-L symptom was analyzed; comparison was made between the normal group and CRI group in the incidence and severity of each MDASI-L symptom.Results The incidence of CRI among the lung canar patients during chemotherapy was 68.4% ( 106/155 ) .The lung canar patients during chemotherapy were higher than the national norms in the score of each PSQI factor and PSQI score ( P<0.05 ) .Significant correlation was noted between PSQI score and fatigue, distress, loss of appetite, numbness, being short of breath, nausea, pain, loss of weight, constipation, chest congestion, and vomiting ( P<0.05 ) .The CRI group was higher than the normal group in the incidence of nausea and being short of breath ( P<0.05 ); two symptoms in MDASI-L questionnaire; the two groups were not significantly different in other MDASI-L symptoms ( P>0.05 ) .The CRI group was severer than the normal group in fatigue, nausea, distress, being short of breath, loss of appetite and conspitation ( P<0.05 ); the two groups were not significantly different in the severity of other MDASI-L symptoms (P>0.05) .Conclusion The incidence of CRI in lung cancer patients during chemotherapy is high.Cancer -related symptoms, including fatigue, nausea, distress, being short of breath, loss of appetite and constipation, should be assessed and precautioned.The alleviation of CRI may mitigate relevant symptoms of tumor.关键词
肺肿瘤/入睡和睡眠障碍/问卷调查Key words
Lung neoplasms/Sleep initiation and maintenance disorders/Questionnaires分类
医药卫生引用本文复制引用
魏婷婷,陈小岑,侯云霞,阎玲,王平..肺癌化疗患者癌因性失眠及肿瘤相关症状调查研究[J].中国全科医学,2015,(21):2564-2567,2572,5.基金项目
天津市抗癌重大专项攻关计划 （）
