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系统性红斑狼疮动物模型研究进展

阎雨 方莲花 杜冠华

中国实验动物学报Issue(4):428-433,6.
中国实验动物学报Issue(4):428-433,6.DOI:10.3969/j.issn.1005-4847.2015.04.019

系统性红斑狼疮动物模型研究进展

Research progress of animal models of systemic lupus erythematosus

阎雨 1方莲花 1杜冠华1

作者信息

  • 1. 中国医学科学院·北京协和医学院药物研究所药物靶点研究和新药筛选北京市重点实验室,北京 100050
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摘要

Abstract

Systemic lupus erythematosus ( SLE) is a chronic multisystem relapsing-remitting autoimmune disease, which affects human health seriously.There are numerous animal models that have long been employed in an effort to un-derstand the mechanism and treatment of SLE.Animal models of SLE were reviewed and compared in this paper, to provide references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic crite-ria, searching for targeted treatment interventions and developing potential therapeutic drugs.

关键词

系统性红斑狼疮/小鼠/动物模型

Key words

Systemic lupus erythematosus/Murine/Animal models

分类

生物科学

引用本文复制引用

阎雨,方莲花,杜冠华..系统性红斑狼疮动物模型研究进展[J].中国实验动物学报,2015,(4):428-433,6.

基金项目

“重大新药创制”科技重大专项(2013ZX09103-001-008,2012ZX09103-101-078,2013ZX09508104)。 ()

中国实验动物学报

OA北大核心CSCDCSTPCD

1005-4847

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