摘要
Abstract
Objective:To explore the clinical effect of the emergency treatment for patients with moderate and severe acute organophosphorus pesticide poisoning,and to provide reference for clinical diagnosis and treatment.Method:52 patients with moderate and severe acute organophosphorus pesticide poisoning admitted to our hospital from January 2012 to March 2014 were selected and divided into the control group for 22 cases and the observation group for 30 cases according to different ways of treatment.The control group was directly sent to hospital for treatment by family members,the observation group was given prehospital emergency guidance and prehospital emergency.The treatment of general situation, complications and clinical efficacy between the two groups were compared.Result:After prehospital emergency,the ICU length of hospital stay in the observation group was (49.6±6.4)h,which was significantly shorter than (71.5±6.3)h in the control group,the dosage of Atropine and Pralidoxime Iodide were (191±42)mg and(4.9±3.3)g,which were significantly less than (327±81)mg and(7.6±2.1)g in the control group,the differences were statistically significant(P<0.05).The incidence of respiratory failure in the observation group was 6.7%, which was significantly lower than 50.0% in the control group,the complication rate of the observation group was 13.3%,which was significantly lower than 63.6% of the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of intermediate syndrome between the two groups(P>0.05).The average symptoms disappear time,atropinization time and ChE recovery time of the observation group were (78.1±8.3)min,(3.1±1.3)min,(71.1±45.2) min,which were significantly shorter than (244.3±51.2)min,(5.9±4.2)min,(133.1±49.3)min of the control group,the differences were statistically significant(P<0.05).In the observation group,the death cases were 2 cases before admission and 2 cases died after admission,the total mortality was 13.3%,in the control group,the death cases were 6 cases before admission and 3 cases died after admission,the total mortality was 40.9%,the difference was statistically significant(P<0.05).Conclusion:Prehospital emergency treatment in patients with severe acute organophosphorus pesticide poisoning can effectively improve the rescue efficiency, improve the clinical effect and reduce the number of deaths,is worthy of further clinical research and application.关键词
前急救/急性有机磷农药中毒/中重度/临床疗效Key words
Prehospital emergency/Acute organophosphorus pesticide poisoning/Moderate and severe/clinical effect
