中国医药科学Issue(13)：208-210,3.
消银颗粒治疗寻常型银屑病的效果及对免疫系统的影响
Influence on immune system and effect of Xiaoying granules in the treatment of psoriasis vulgaris Influence on immune system and effect of Xiaoying granules in the treatment of psoriasis vulgaris
摘要
Abstract
Objective To explore the influential effect on immune system of Xiaoying granules in the treatment of psoriasis vulgaris.Methods100 patients with psoriasis vulgaris who were admitted to our hospital from May 2013 to September 2014 were randomly divided to control group and observation group, and they were treated with conventional method and Xiaoying granules. Clinical effect, adverse drug reaction and influence on immune factors such as matrix metalloproteinases-9 (MMP-9), macrophage migration inhibitory factor (MIF) and tumor necrosis factor(TNF-α)of two groups were compared.Results The total effective rate of observation group 96.00%, which was significantly higher than 82.00% of control group, and the difference was statistically significant (P<0.05). There was no statistical significance in the incidence rate of adverse drug reactions such as skin itch, abnormal liver function, gastrointestinal reaction and desquamation of skin of observation group (P>0.05). The number of positive cases of MMP-9, MIF and TNF-α of observation group was significantly larger than that of control group, and the difference was statistically significant(P<0.05).ConclusionXiaoying granules in the treatment of psoriasis vulgaris can improve clinical effect by improving patients' immune system with significant clinical effect, which was worthy of clinical promotion and application.关键词
消银颗粒/寻常型/银屑病/免疫Key words
Xiaoying granulesl/Vulgaris/Psoriasis/Immune分类
医药卫生引用本文复制引用
李建辉,李丹,曾兰芳..消银颗粒治疗寻常型银屑病的效果及对免疫系统的影响[J].中国医药科学,2015,(13):208-210,3.基金项目
广东省东莞市科技局科技计划项目（2014105101187）。 （）
