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不同粒径三黄粉粉体学性质及体外溶出度比较

范凌云 王振恒 余琰 高建德 魏舒畅

中国中医药信息杂志Issue(9):91-94,4.
中国中医药信息杂志Issue(9):91-94,4.DOI:10.3969/j.issn.1005-5304.2015.09.025

不同粒径三黄粉粉体学性质及体外溶出度比较

Comparison of Micromeritics Properties and External Dissolution Rates ofSanhuang Powder with Different Particle Sizes

范凌云 1王振恒 1余琰 1高建德 1魏舒畅1

作者信息

  • 1. 甘肃中医药大学,甘肃 兰州 730000
  • 折叠

摘要

Abstract

Objective To compare the micromeritics properties and external dissolution rates of Sanhuang Powder in different particle sizes;To provide references for its direct use and application as raw materials for TCM preparation.Methods Particle size, bulk density, tap density, angle of repose, and hygroscopicity ofSanhuang micro-powder and common powder were investigated and evaluated. External dissolution rates ofSanhuang micro-powder and common powder were detected by ultraviolet spectrophotometry.Results The flowability of bothSanhuang micro-powder and common powder were not very well. With the sizes decreasing, the hygroscopicity of micro-powder became stronger. The external dissolution ofSanhuang micro-powder was more sufficient and much more quickly than common powder.Conclusion Properties ofSanhuang micro-powder and common powder are obviously different.Sanhuang micro-powder has stronger hygroscopicity and worse flowability compared with common powder. However, external dissolution ofSanhuang micro-powder is more sufficient and much more quickly than common powder. WhenSanhuang micro-powder is used directly and used as raw materials for TCM preparation, much more discretion should be considered.

关键词

三黄粉/超微粉碎/粉体学性质/吸湿性/体外溶出度

Key words

Sanhuang Powder/superfine grinding/micromeritics property/hygroscopicity/external dissolution rate

分类

医药卫生

引用本文复制引用

范凌云,王振恒,余琰,高建德,魏舒畅..不同粒径三黄粉粉体学性质及体外溶出度比较[J].中国中医药信息杂志,2015,(9):91-94,4.

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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