摘要
Abstract
Objective To discuss correlation of diabetic cardiomyopathy AT1-AAs and VEGF. Methods Thirty-three patients with diabetic cardiomyopathy, 35 patients with type 2 diabetes and 30 cases healthy people were selected for the study. AT1-AAs and VEGF were detected, and the correlation was analyzed. Results Serum VEGF levels in dia-betic cardiomyopathy patients was significantly higher than the diabetic group and the control group, and the difference was statistically significant (P<0.01);VEGF levels in diabetic group was significantly higher than control group, and the difference was statistically significant (P<0.01). Serum VEGF levels in diabetic cardiomyopathy patients with severe car-diomyopathy expand was the highest, followed by patients with moderate to expand, the lowest in patients with mild to expand, and the difference was statistically significant (P<0.01). Serum VEGF levels in patients with positive AT1-AAs were significantly higher in patients with negative AT1-AAs,and the difference was statistically significant (P<0.01). Correlation analysis showed significant correlation between AT1-AAs and VEGF(r=0.271, P<0.01). Conclusion Serum VEGF level and AT1-AAs are relevant with the incidence and development of diabetic cardiomyopathy, and AT1-AAs and VEGF levels are correlated.关键词
糖尿病心肌病/血管内皮生长因子/血管紧张素域1型受体自身抗体Key words
Diabetic cardiomyopathy/VEGF/AT1-AAs分类
医药卫生
