摘要
Abstract
Objective To investigate the clinical effect and prognostic affecting factors of stereotactic surgery in patients with hypertensive cerebral hemorrhage. Methods 90 cases with hypertensive cerebral hemorrhage were selected as the research objects from February 2011 to April 2013 in our department. They were randomly divided into the routine group receiving con‐ventional surgery and the study group treated by stereotactic surgery ,45 cases in each group. Bleeding volume ,clinical efficacy and activity of daily living (ADL ) scores ,cellular changes in immunological parameters were compared between two groups , and prognostic factors in both groups were analyzed.Results Bleeding was significantly decreased in both routine group and the study group at 1 ,2 and 4 weeks after treatment (P < 0.05) ,and bleeding in the study group only accounted for 49.88% , 37.18% and 23.98 % of the traditional group ,which was significantly lower than that in the routine group (P< 0.05). Over‐all effective rate of routine group was 44.44% ,which was also significantly lower than that of the study group (77.78% ) (P<0.05). In addition ,self‐care ability ,positive cell ratio of CD3 + and CD4 in study group significantly improved compared with the traditional group (P< 0.05) ;but positive cell ratio of CD8 + did little change (P> 0.05) ,and no significant difference was found between two groups (P> 0.05). Univariate and multivariate analysis showed that the hypertension duration (β= 0.761 ,P= 0.032) ,GCS scores (β = 0.851 , P = 0.025) and BMI (β = 2.59 , P = 0.014) were independent risk factors in routine group ;while independent risk factors were GCS scores (β = 0.799 , P = 0.010) and hypertension duration (β = 0.616 , P =0.004) in study group. Conclusion Compared to conventional conservative treatment ,stereotactic surgery can significantly im‐prove clinical symptoms in patients with hypertensive cerebral hemorrhage ,and improve the prognosis of the disease.关键词
高血压脑出血/立体定向手术/预后/影响因素Key words
Hypertensive intracerebral hemorrhage/Stereotactic surgery/Prognosis/Affecting factors分类
医药卫生
