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颅骨钻孔尿激酶溶解引流术治疗脑出血的疗效分析

马金波 李伟 陈慧源

中国实用神经疾病杂志Issue(18):8-9,2.
中国实用神经疾病杂志Issue(18):8-9,2.

颅骨钻孔尿激酶溶解引流术治疗脑出血的疗效分析

Clinical efficacy analysis of cranial drilling and urokinase dissolve drainage in the treatment of cerebral hemor-rhage

马金波 1李伟 1陈慧源2

作者信息

  • 1. 河北唐山市开滦总医院急诊科 唐山 063000
  • 2. 河北唐山市开滦赵各庄医院神经外科 唐山 063101
  • 折叠

摘要

Abstract

Objective To compare clinical efficacy of cranial drilling and urokinase dissolve drainage versus small bone window craniotomy in patients with hypertensive cerebral hemorrhage .Methods 86 cases of hypertensive cerebral hemorrhage were randomly divided into small bone window craniotomy group (group A) and cranial drilling and urokinase dissolve drainage group (group B) .Patients in group A under general anesthesia ,we evacuated the hematoma using microsurgical instruments under direct vision .Patients in group B under local anesthesia ,we placed the drainage tube into the hematoma with the help of brain needle ,then dissolved hematoma supplemented by urokinase .Operation time ,hospitalization stay ,postoperative bleeding and postoperative complications ,the recent and long‐term curative effect after operation of two groups were observed and com‐pared in two groups .Results The operation time and hospital stay of group A were significantly longer than that of group B (P<0 .05);The hematoma clearance rate of group A was obviously better than that of group B (P<0 .05);Although patients in two groups complicated with lung infection and gastrointestinal bleeding ,there was no statistical difference between the two groups (P>0 .05) .After 1‐month operation ,patients in group A had severer nerve function defect degree than those in group B (P<0 .05);in addition ,the Barthel scores of daily life ability of two groups showed no significant difference after 6‐month operation(P>0 .05) .Conclusion Cranial drilling and urokinase dissolve drainage operation is simply feasible with shorter hos‐pitalization stay and better short‐term neural functional recovery .

关键词

脑出血/尿激酶/引流术

Key words

Cerebral hemorrhage/Urokinase/Drainage

分类

医药卫生

引用本文复制引用

马金波,李伟,陈慧源..颅骨钻孔尿激酶溶解引流术治疗脑出血的疗效分析[J].中国实用神经疾病杂志,2015,(18):8-9,2.

中国实用神经疾病杂志

1673-5110

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