健康研究Issue(4)：409-411,3.DOI:10.3969/j.issn.1674-6449.2015.04.017
龈沟液 OPG／RANKL 表达与慢性牙周炎患者龈沟出血指数的相关性
The correlation of OPG/RANKL expression level of gingival crevicular fluid to sulcus bleeding index in patients with chronic periodontitis
吕旭君1
作者信息
- 1. 浙江省宁波市北仑区第二人民医院 口腔科，浙江 宁波315809
- 折叠
摘要
Abstract
Objective To examine the relationship between the level of osteoprotegerin ( OPG) and receptor activator of nuclear factor-KB ligand ( RANKL) expression and sulcus bleeding index.Method The gingival crevicular fluid of 37 patients with chronic periodontitis ( chosen as the experimental group ) and 31 healthy volunteers were abstracted with moisture absorption paper point method.Their OPG and RANKL expression level were detected with immunofluorescence test and the correlation of OPG/RANKL expression and sulcus bleeding index were analyzed with simple linear regression. Findings Compared with the control group, the OPG and OPG/RANKL expression level were lower significantly and the RANKL expression level were higher significantly (P<0.001).Negative correlation was found between the OPG/RANKL expression level and sulcus bleeding index (y=-3.7755x +3.6212,R2 =0.6651,P<0.05).Conclusion OPG/RANKL/RANK system is involved in the occurrence and development of chronic periodontitis.It can be used as an objective index to measure the degree of inflammatory bleeding.关键词
牙周炎/龈沟液/OPG/RANKL/出血指数Key words
periodontitis/gingival crevicular fluid/OPG/RANKL/bleeding index分类
医药卫生引用本文复制引用
吕旭君..龈沟液 OPG／RANKL 表达与慢性牙周炎患者龈沟出血指数的相关性[J].健康研究,2015,(4):409-411,3.
