林产化学与工业Issue(4)：125-130,6.DOI:10.3969/j.issn.0253-2417.2015.04.020
响应面法优化二氢杨梅素半合成杨梅素
Optimization of Semisynthetic Myricetin from Dihydromyricetion by Response Surface Process
摘要
Abstract
Dihydromyricetion( DMY) , which was abundant and easily extracted from the leaves of Ampelopsis grossedentata, was used as the semisynthetic sources for myricetin( MYR) . The structure of MYR was characterized by IR, 1H NMR and 13C NMR. Based on the results of the single factor experiments, response surface methodology( RSM) was applied to further optimize the synthesis conditions with pyridine volume fraction, and temperature, solid-liquid-ratio as the impact factors and MYR yield as the response value. The most suitable synthesis conditions of MYR were determined as follows: pyridine volume fraction 66. 6%, temperature 90. 4 ℃ and solid-liquid ratio 20. 88(g∶L). The MYR yield was 76. 63%, and the relative error with the predictive value of 76. 48% was 0. 19%.关键词
二氢杨梅素/半合成/杨梅素/响应面分析Key words
dihydromyricetion/semisynthetic/myricetin/response surface methodology分类
化学化工引用本文复制引用
..响应面法优化二氢杨梅素半合成杨梅素[J].林产化学与工业,2015,(4):125-130,6.基金项目
湖南省高校科技创新团队支持计划(湘教通(2010)212号) （湘教通(2010）
