陕西医学杂志Issue(9)：1124-1126,3.DOI:10.3969/j.issn.1000-7377.2015.09.008
单纯性肥胖并脂肪肝患儿脂联素及炎性因子水平测定
Evaluations on adiponectin and inflammatory factor levels and their clinical significance of nonalcoholic fatty liver in obese children
摘要
Abstract
Objective :To observe changes of blood lipids ,transaminase and other related parameters , and to investigate actions of inflammatory factors on the occurrence of nonalcoholic fatty liver in obese children . Methods :A total of 121 obese children and 31 healthycontrols were enrolled in this study .Obesity was defined as a body mass index exceeding the 95thpercentile for the patients'age and sex .Nonalcoholic fatty liver was diagnosed via ultrasonographic examin ‐ation .Obese children were divided into two groups ,fatty liver group(C group) and non‐fatty liver group(B group) ,31 healthy children as control group(A group) .The height ,weight ,BMI ,waistline , hipline ,waist‐to‐hip ratio and Waist to height ratio were measured and documented for every child .Blood lipids , transaminase ,hs‐CRP ,adiponectin and TNF‐α were also measured .Results : There are significant differences in BMI ,waistline and waist‐to‐hip ratio between any two groups(P< 0 .05) .Waist to height ratio ,TG and TCH was different significantly between B /A ,and C /A(P< 0 .05) .AST and ALT were also found different significantly be‐tween any two groups(P< 0 .05) ,and levels of transaminases increased gradually among A ,B and C groups .Con‐clusion :In this study ,levels of AST and ALT were found higher than controls in early phase of nonalcoholic fatty liver in obese children .Enhancement of inflammatory reaction was in relation with fatty liver .关键词
肥胖症/并发症/脂肪肝/病因学/脂肪肝/血液/血糖/代谢/甘油三酯类/代谢/儿童Key words
Obesity/complication/Fatty liver/etiology/Fatty/liver/blood/Blood glucose/metabo-lism/Diglycerides/metabolism/Child分类
医药卫生引用本文复制引用
李华,肖延风,尹春燕,楚海平..单纯性肥胖并脂肪肝患儿脂联素及炎性因子水平测定[J].陕西医学杂志,2015,(9):1124-1126,3.基金项目
国家自然科学基金项目 （）
