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基于石墨烯构筑的三维组织工程支架材料

王欣 李鹏 王赞 徐海峰 董福平 陈浩 姜宏宇 Klaud D Jandt

中国组织工程研究Issue(34):5523-5529,7.
中国组织工程研究Issue(34):5523-5529,7.DOI:10.3969/j.issn.2095-4344.2015.34.022

基于石墨烯构筑的三维组织工程支架材料

Three-dimensional tissue engineering scaffolds based on graphene

王欣 1李鹏 2王赞 1徐海峰 3董福平 4陈浩 4姜宏宇 1Klaud D Jandt3

作者信息

  • 1. 吉林大学材料科学与工程学院,吉林省长春市130012
  • 2. 耶拿弗里德里希席勒大学材料科学与技术系,耶拿,07743,德国
  • 3. 吉林大学白求恩第一医院神经内科,吉林省长春市 130021
  • 4. 耶拿弗里德里希席勒大学材料科学与技术系,耶拿,07743,德国
  • 折叠

摘要

Abstract

BACKGROUND:Based on the chemical composition and physical structure, graphene nanosheets can be used to form a very similar biological micro-environment to the extracelular matrix. OBJECTIVE:To review the preparation, cytocompatibility and cel interaction of graphene-based three-dimensional scaffolds in recent years. METHODS:A computer-based search of CNKI, ACS-ACS Publications, Elsevier Science, Nature and PNAS was performed to retrieve articles related to the type, preparation and application of biomedical graphene in tissue engineering. RESULTS AND CONCLUSION:Graphene and its derivatives are made as a module, and based on its two-dimensional structural characteristics or functional groups enriched in oxidized graphene, graphene nanosheets can be assembled in different ways to build a three-dimensional macroscopic structure that is easy to compound other functional materials. Compared with a single graphene sheet or carbon nanomaterials, three-dimensional macroscopic graphene and its composite materials wil be more likely to form new and unique structures and properties, which have more practical values and possess the functions of tissue engineering scaffolds.

关键词

生物材料/纳米材料/石墨烯/三维支架/细胞相容性/组织工程支架

Key words

Graphite/Tissue Engineering/Extracellular Matrix

分类

医药卫生

引用本文复制引用

王欣,李鹏,王赞,徐海峰,董福平,陈浩,姜宏宇,Klaud D Jandt..基于石墨烯构筑的三维组织工程支架材料[J].中国组织工程研究,2015,(34):5523-5529,7.

基金项目

留学人员科技创新创业项目优秀类(3D510A941460)和吉林省科技厅基础项目(201215025)@@@@ the Outstanding Technological Innovation and Entrepreneurship Program of Overseas Students, No.3D510A941460 (3D510A941460)

the Base Projects of Science and Technology Department of Jilin Province, No.201215025 ()

中国组织工程研究

OA北大核心CSTPCD

2095-4344

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