中国组织工程研究Issue(34):5523-5529,7.DOI:10.3969/j.issn.2095-4344.2015.34.022
基于石墨烯构筑的三维组织工程支架材料
Three-dimensional tissue engineering scaffolds based on graphene
摘要
Abstract
BACKGROUND:Based on the chemical composition and physical structure, graphene nanosheets can be used to form a very similar biological micro-environment to the extracelular matrix. OBJECTIVE:To review the preparation, cytocompatibility and cel interaction of graphene-based three-dimensional scaffolds in recent years. METHODS:A computer-based search of CNKI, ACS-ACS Publications, Elsevier Science, Nature and PNAS was performed to retrieve articles related to the type, preparation and application of biomedical graphene in tissue engineering. RESULTS AND CONCLUSION:Graphene and its derivatives are made as a module, and based on its two-dimensional structural characteristics or functional groups enriched in oxidized graphene, graphene nanosheets can be assembled in different ways to build a three-dimensional macroscopic structure that is easy to compound other functional materials. Compared with a single graphene sheet or carbon nanomaterials, three-dimensional macroscopic graphene and its composite materials wil be more likely to form new and unique structures and properties, which have more practical values and possess the functions of tissue engineering scaffolds.关键词
生物材料/纳米材料/石墨烯/三维支架/细胞相容性/组织工程支架Key words
Graphite/Tissue Engineering/Extracellular Matrix分类
医药卫生引用本文复制引用
王欣,李鹏,王赞,徐海峰,董福平,陈浩,姜宏宇,Klaud D Jandt..基于石墨烯构筑的三维组织工程支架材料[J].中国组织工程研究,2015,(34):5523-5529,7.基金项目
留学人员科技创新创业项目优秀类(3D510A941460)和吉林省科技厅基础项目(201215025)@@@@ the Outstanding Technological Innovation and Entrepreneurship Program of Overseas Students, No.3D510A941460 (3D510A941460)
the Base Projects of Science and Technology Department of Jilin Province, No.201215025 ()