中国感染控制杂志Issue(8)：530-534,5.DOI:10.3969/j.issn.1671-9638.2015.08.006
新生儿重症监护病房器械相关感染流行病学多中心研究
Multicenter study on epidemiology of device-associated infection in neonatal intensive care units
摘要
Abstract
Objective To investigate the epidemiological characteristics of device-associated infection (DAI)in neonatal intensive care units(NICUs)of tertiary first-class hospitals in China,and provide scientific evidence for the prevention and control of neonatal DAI.Methods Neonates in NICUs at 17 hospitals of 9 provinces from October 2013 to September 2014 were selected for multicenter study,DAI was surveyed prospectively according to the uni-form diagnostic criteria and methods.Results A total of 12 998 neonates were monitored,the total patient-days were 126 125 d,13 cases of central line-associated bloodstream infection (CLABSI)and 70 cases of ventilator-asso-ciated pneumonia (VAP)occurred,central line utilization rate was 15.56%,incidence of CLABSI was 0.66/1 000 device-days;ventilator utilization rate was 7.67%,incidence of VAP was 7.23/1 000 device-days.Utilization rates of central line and respirator in neonates with body weight ≤ 1 000 g was the highest,which were 61 .06% and 29.91 % respectively;In NICUs with 20-30 beds,utilization rate of central line was the highest(16.67%),and res-pirator was the lowest(4.11 %);of hospitals in different regions,central line and respirator utilization rate in south-west China was the highest.Of different sizes of ICUs,VAP per 1 000 device-days was the lowest in NICUs with 20-30 beds(2.36 ‰).Difference in incidence of CLABSI and VAP per 1 000 device-days in neonates at NICUs of different regions were significantly different;incidence of CLABSI and VAP per 1 000 device-days was highest in southern China(2.68 ‰ and 31 .06‰ respectively),followed by southwest region.Of different quarters,incidence of CLABSI,and VAP per 1 000 device-days were not significantly different(all P >0.05).Conclusion Device utili-zation rate and incidence of DAI in China are both high,and are different in neonates of different birth weight,at different sizes of NICUs,as well as different regions,monitoring should be intensified,prevention and control measures should be implemented according to infection characteristics.关键词
新生儿监护病房/中心静脉导管相关感染/呼吸机相关肺炎/流行病学/多中心研究Key words
neonatal intensive care unit/central line-associated bloodstream infection/ventilator-associated pneu-monia/epidemiology/multicenter study分类
医药卫生引用本文复制引用
任军红,杨芸,刘运喜,建国,陆群,贾会学,李六亿,殷环,吴安华,胡必杰,张秀月,侯铁英,宗志勇,李卫光,杨怀..新生儿重症监护病房器械相关感染流行病学多中心研究[J].中国感染控制杂志,2015,(8):530-534,5.基金项目
中国医院协会医院感染预防与控制能力建设项目 （）
