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Onyx胶栓塞在脑动静脉畸形患者临床安全性及预后探究

唐建建 张紫寅 周建 马春阳 王子珍 黄秋虎

中国医药科学Issue(16):116-118,138,4.
中国医药科学Issue(16):116-118,138,4.

Onyx胶栓塞在脑动静脉畸形患者临床安全性及预后探究

Clinical application and safety inquiry of Onyx glue embolization in patients with cerebral arteriovenous malformation

唐建建 1张紫寅 2周建 3马春阳 3王子珍 3黄秋虎3

作者信息

  • 1. 四川省金堂县第一人民医院神经外科,四川金堂 610400
  • 2. 海南医学院附属医院神经外科,海南海口 570102
  • 3. 海南医学院附属医院神经外科,海南海口 570102
  • 折叠

摘要

Abstract

Objective To observe and explore the clinical value and safety of Onyx glue embolization in patients with cerebral arteriovenous malformation(CAVM). Methods 96 patients with CAVM in this hospital from June 2010 to January 2014 were selected, all the patients were randomized divided into two groups, 48 cases in the observation group and 48 cases in the control group, the observation group were treated with Onyx glue embolization, while the control group were treated with NBCA glue embolization. Occlusion rate ≥80%, recurrence rate, the average reduced volume, postoperative recovery time and hospital stay, as well as complications were observed in the two groups after treatment.ResultsThe ratio of occlusion rate≥80% and recurrence in observation group was 87.5%(42/48) and 0, while was 66.7%(32/48) and 12.5%(6/48) in the control group, the difference was statistically significance(P<0.05); the average reduced volume, postoperative recovery time and hospitalization time were (12.5±2.9)cm3,(25.4±4.9) h and (15.8±1.9)d in observation group, while was(9.6±2.4)cm3, (25.9±4.6)h and (16.2±1.8)d in the control group, the difference the average reduced volume between the two groups was statistically significant (P<0.05); complication rate was 4.2%(2/48) in the observation group, and was 10.4%(5/48) in the control group, the difference was not statistically significant(P>0.05).Conclusion Onyx glue embolization can significantly improve the clinical symptoms of CAVM patients, with significant effect, thus is safe and effective therapy.

关键词

Onyx胶/栓塞治疗/脑动静脉畸形

Key words

Onyx glue/Embolization/CAVM

分类

医药卫生

引用本文复制引用

唐建建,张紫寅,周建,马春阳,王子珍,黄秋虎..Onyx胶栓塞在脑动静脉畸形患者临床安全性及预后探究[J].中国医药科学,2015,(16):116-118,138,4.

中国医药科学

2095-0616

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